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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 17.58
Human Site: S199 Identified Species: 27.62
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 S199 C L G T D E D S Q D S S D G I
Chimpanzee Pan troglodytes XP_508558 546 61795 S232 C L G T D E D S Q D S S D G I
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 S138 D Q P L S S S S C L Q P N H R
Dog Lupus familis XP_540849 546 61797 S232 C L G T D E D S Q D S S D G I
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 S199 C L G T D E D S Q D S S D G I
Rat Rattus norvegicus Q5XI06 458 52614 K154 D E I N H V Q K T Y A E M D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 L271 V G V Y R E E L S A I V A P L
Zebra Danio Brachydanio rerio NP_001013327 538 61712 S224 Y L P P G E D S Q D S S D G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 G229 S G A A N D D G D G S Q D G K
Honey Bee Apis mellifera XP_396552 453 52544 G149 D G P P Q T P G P R P T G S L
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 R154 S G S T P S L R G S M S M V G
Sea Urchin Strong. purpuratus XP_786024 440 50807 A135 L D I L N V N A P R Q T G S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 H141 T S L K M T R H Q K R K I D E
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 H141 I K D E N I S H E D E I K K L
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 E185 E I D M D E D E I P A A K K Q
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 6.6 100 N.A. 100 0 N.A. N.A. N.A. 6.6 73.3 N.A. 26.6 0 13.3 0
P-Site Similarity: 100 100 13.3 100 N.A. 100 6.6 N.A. N.A. N.A. 20 73.3 N.A. 40 13.3 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 20
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 0 7 0 7 14 7 7 0 0 % A
% Cys: 27 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 20 7 14 0 34 7 47 0 7 40 0 0 40 14 0 % D
% Glu: 7 7 0 7 0 47 7 7 7 0 7 7 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 27 27 0 7 0 0 14 7 7 0 0 14 40 7 % G
% His: 0 0 0 0 7 0 0 14 0 0 0 0 0 7 0 % H
% Ile: 7 7 14 0 0 7 0 0 7 0 7 7 7 0 34 % I
% Lys: 0 7 0 7 0 0 0 7 0 7 0 7 14 14 7 % K
% Leu: 7 34 7 14 0 0 7 7 0 7 0 0 0 0 20 % L
% Met: 0 0 0 7 7 0 0 0 0 0 7 0 14 0 7 % M
% Asn: 0 0 0 7 20 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 20 14 7 0 7 0 14 7 7 7 0 7 7 % P
% Gln: 0 7 0 0 7 0 7 0 40 0 14 7 0 0 7 % Q
% Arg: 0 0 0 0 7 0 7 7 0 14 7 0 0 0 7 % R
% Ser: 14 7 7 0 7 14 14 40 7 7 40 40 0 14 0 % S
% Thr: 7 0 0 34 0 14 0 0 7 0 0 14 0 0 0 % T
% Val: 7 0 7 0 0 14 0 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _